Phage display identification of immunodominant epitopes and autoantibodies in autoimmune diseases
Marco Palma
The phage display is a powerful technique to identify pathogenic binding sites implicated in autoimmune diseases (ADs). With chimeras of binding peptides can be identified amino acid residues implicated in the binding and defined more precisely the pathogenic epitope such as in the α3(IV)NC1 domain of Goodpasture disease. Epitope sharing….
