Phage display identification of immunodominant epitopes and autoantibodies in autoimmune diseases

Marco Palma

The phage display is a powerful technique to identify pathogenic binding sites implicated in autoimmune diseases (ADs). With chimeras of binding peptides can be identified amino acid residues implicated in the binding and defined more precisely the pathogenic epitope such as in the α3(IV)NC1 domain of Goodpasture disease. Epitope sharing….

Phage display strategy against outbreaks of unknown pathogens: learning from the SARS-CoV-2 pandemic.

Marco Palma

The experience with SARS-CoV-2 that spread rapidly throughout the world makes us realize we need protocols to act quickly against emerging pathogens. The immune system of recovering patients provided protection against any pathogen by producing antibodies against immunogenic epitopes…